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Leto's performance as a transgender woman in Dallas Buyers Club (2013) earned him an Academy Award, a Golden Globe Award, and a Screen Actors Guild Award for Best Supporting Actor.
Leto is considered to be a method actor, known for his constant devotion to and research of his roles.
Their debut album, 30 Seconds to Mars (2002), was released to positive reviews but only to limited success.
The band achieved worldwide fame with the release of their second album A Beautiful Lie (2005).
In 2016, he played the DC Comics supervillain Joker in the DC Extended Universe film Suicide Squad.Their following releases, This Is War (2009) and Love, Lust, Faith and Dreams (2013), received further critical and commercial success. His parents divorced when he was a child, and he and his older brother, Shannon Leto, lived with their mother and their maternal grandparents, Ruby (Russell) and William Lee Metrejon.He often remains completely in character for the duration of the shooting schedules of his films, even to the point of adversely affecting his health.Leto is the lead vocalist, multi-instrumentalist and main songwriter for Thirty Seconds to Mars, a band he formed in 1998 in Los Angeles, California, with his older brother Shannon Leto.He made his film debut in How to Make an American Quilt (1995) and received critical praise for his performance in Prefontaine (1997).
Leto played supporting roles in The Thin Red Line (1998), Fight Club (1999) and American Psycho (2000), as well as the lead role in Urban Legend (1998), and earned critical acclaim after portraying heroin addict Harry Goldfarb in Requiem for a Dream (2000).